Human Tumour Markers: Biological Basis and Clinical Relevance
نویسندگان
چکیده
منابع مشابه
Clinical Significance of Tumour Markers
Tumour markers are biochemical indicators of the presence of a tumour, which are selectively produced by the neoplastic tissue and released into blood or in other body fluids. They are widely accepted and applied to the management of patients with cancer since the introduction of diagnostic immunopathology. Tumour markers include oncofetal antigens (AFP), glycoproteins (CEA), placental proteins...
متن کاملNeuroblastoma tumour genetics: clinical and biological aspects.
Neuroblastoma tumour cells show complex combinations of acquired genetic aberrations, including ploidy changes, deletions of chromosome arms 1p and 11q, amplification of the MYCN oncogene, and-most frequently-gains of chromosome arm 17q. Despite intensive investigation, the fundamental role of these features in neuroblastoma initiation and progression remains to be understood. Nonetheless, grea...
متن کاملTauopathies with parkinsonism: clinical spectrum, neuropathologic basis, biological markers, and treatment options.
Tauopathies with parkinsonism represent a spectrum of disease entities unified by the pathologic accumulation of hyperphosphorylated tau protein fragments within the central nervous system. These pathologic characteristics suggest shared pathogenetic pathways and possible molecular targets for disease-modifying therapeutic interventions. Natural history studies, for instance, in progressive sup...
متن کاملMolecular basis and clinical application of biological markers of bone turnover.
An ideal battery of tests would include indices of bone resorption and formation. They should be unique to bone, reflect total skeletal activity, and should correlate with traditional measures of bone remodeling activity, such as radiocalcium kinetics, histomorphometry, or changes in bone mass. Factors that confound their measurement, such as circadian rhythms, diet, age, sex, bone mass, liver ...
متن کاملClinical and Biological Markers in Hypereosinophilic Syndromes
Hypereosinophilic syndromes (HES) are rare, heterogeneous syndromes characterized by markedly elevated eosinophil counts in the blood and/or tissue and evidence of eosinophil-associated pathology. Although parasitic infections, drug hypersensitivity, and other disorders of defined etiology can present as HES (associated HES), treatment is directed at the underlying cause rather than the eosinop...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 1984
ISSN: 0021-9746
DOI: 10.1136/jcp.37.6.719-a